Symbol Name ID |
Bax
BCL2-associated X protein MGI:99702 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating IgG2 level |
Defective B cell differentiation |
Abnormal B cell count |
Decreased proportion of CD4-positive helper T cells |
T lymphocytopenia |
Lymphopenia |
Leukemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Sinusitis |
Hypoplasia of the thymus |
Recurrent lower respiratory tract infections |
Recurrent bronchitis |
Disease(s) Associated with BAX | |||||||||||||||
acute lymphoblastic leukemia | |||||||||||||||
ataxia telangiectasia |
Mouse Phenotypes | increased thymocyte number |
enlarged spleen |
increased transitional stage B cell number |
increased B cell number |
abnormal plasma cell morphology |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased IgG2a level |
increased IgG level |
increased IgM level |
increased immunoglobulin level |
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Availability | Mouse Genotype | ||||||||||||
Baxtm1Sjk/Baxtm1Sjk | |||||||||||||
Tg(Igk-V21-Bax)1967Bvn/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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